INVESTIGATE THE RELATIONSHIP BETWEEN PLASMA GGT WITH METABOLIC SYNDROME IN MIDDLE-AGED PATIENTS WITH ISCHEMIC STROKE

Tóm tắt

A prospective study, cross-sectional description of 205 middle-aged patients including 106 outpatients without cerebral stroke and 99 patients with ischemic stroke at Cerebral Stroke center - 108 Military Central Hospital from January 1, 2018 to December 30, 2020.

Results: Metabolic Syndrome (MS) and high blood pressure were correlated with increased risk of cerebral stroke with OR: 4.511, 95%CI: 2.454-8.291, p = 0.000 and OR: 5.078, 95%CI: 4.579-12.579, p = 0.000, respectively. The risk of cerebral stroke was significantly elevated with increased GGT levels, with OR: 3.6, 95%CI: 1.638-7.911, p = 0.001. The patients were men, with increased blood pressure and round the waist leading to suffer from Metabolic syndrome with OR: 7.05, 95%CI: 2.71-18.34, p = 0.000, OR: 5.714, 95%CI: 1.891-17.264, p = 0.001 and OR: 2.779, 95%CI: 1.226-6.302, p = 0.016, respectively. Increased blood glucose, triglyceride, GGT levels were highly associated with the risk of Metabolic Syndrome with OR: 6.857, 95%CI: 2.551-18.435, p = 0.000, OR: 5.374, 95%CI: 4.724-24.896, p = 0.000 and OR: 3.912, 95%CI: 1.413-10.831, p = 0.007, respectively.

Conclusion: Elevated GGT levels were associated with the risk of Metabolic Syndrome in middle-aged patients with cerebral infarction, with OR: 3.912, 95%CI: 1.413-10.831, p = 0.007.