STUDY ON FREQUENCY OF MUTATIONS FOR HVII REGION OF MITOCHONDRIAL DNA OF VIETNAMESE POPULATION SAMPLES AND APPLICATIONS IN FORENSIC IDENTIFICATION
Từ khóa:
DNA analysis, mitochondrial DNA, frequency.Tóm tắt
There are many mutations in the hypervariable II region in mitochondrial DNA. Determining the frequency of mitochondrial HVII region mutations improves the reliability of identifying human remains using the mitochondrial DNA technique. Our study is mutations in the HVII region in mitochondrial DNA of 300 blood samples that were collected from 300 unrelated Vietnamese individual. Results: Determine 31 mutations in mitochondrial HVII region, in there, frequencies of 24 mutations are low 10% (77.41%), frequencies of mutations are 10-30% (16.14%), frequencies of 2 mutations are high 30% (6.45%).
Tài liệu tham khảo
Phan Van Chi et al. (2006), Study on decoding mitochondrial genomes of Vietnamese ethnic groups and application orientation, State-level project code KC 04-25.
Budowle B, Wilson M.R, DiZinno et al (1999), Mitochondrial DNA regions HV1 and HV1I population data, Forensic Science International l103: 23-35.
Lian Lay Hoong, Koh Chong Lek (2005), “Mitochondrial DNA types in Malaysia Asia Pacific Journal of Molecular Biology and Biotechnology”, AsPac J. Mol. Biol. Biotechnol. Vol.13(2) 79-85.
