ASSESSMENT OF UNWANTED EFFECTS OF CONCURRENT CHEMORADIOTHERAPY FOR NASOPHARYNGEAL CARCINOMA, AT THE NATIONAL OTORHINOLARYNGOLOGY HOSPITAL OF VIETNAM, FROM 2019 TO 2023
DOI:
https://doi.org/10.59459/1859-1655/JMM.330Từ khóa:
Ung thư vòm mũi họng, tác dụng không mong muốn, tỷ lệ đáp ứngTóm tắt
Purpose: Assessment of the unwanted effects of concurrent chemoradiotherapy for nasopharyngeal carcinoma.
Subjects and methods: A retrospective combined prospective study and description of 53 patients with stage II-IVA nasopharyngeal carcinoma, treated with concurrent chemoradiotherapy by the cisplatin regimen on days 1, 22 and 43 at the National Otorhinolaryngology Hospital of Vietnam from 2019 to 2023.
Results: The incidence of grade 3 toxicity on the hematopoietic and non-hematopoietic systems, and late complications occurred at a low rate. Specifically: toxicities of leukopenia and granulocytopenia at grade 3 were 17.0%, and 7.5% respectively; toxicity: dermatitis, mucositis, and, nausea at grade 3 were 3.8%, 18.9%, and 5.7%, respectively. Late complications of xerostoma and skin fibrosis at grade 3 were 18.9% and 1.9%, respectively.
Tài liệu tham khảo
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Chấp nhận đăng 13-12-2023
Ngày xuất bản 28-02-2024