EVALUATION OF ANALGESIC EFFICACY FOLLOWING RENAL TRANSPLANTATION USING BUPIVACAINE-FENTANYL MIXTURE VIA PATIENT-CONTROLLED EPIDURAL ANALGESIA

Các tác giả

  • Tran Dac Tiep Military Hospital 103
  • Trinh Van Duc Military Hospital 103
  • Nguyen Ngoc Thach Military Hospital 103
  • Nguyen Truong An Military Hospital 175
  • Truong Xuan Bach Military Hospital 175

DOI:

https://doi.org/10.59459/1859-1655/JMM.835

Từ khóa:

PCEA, renal transplantation, postoperative analgesia

Tóm tắt

Objectives: To evaluate the analgesic efficacy of a bupivacaine-fentanyl mixture administered via patient-controlled epidural analgesia (PCEA) following renal transplantation.

Subjects and methods: A cross-sectional descriptive study was conducted on 50 patients who underwent renal transplantation at Military Hospital 103 and received postoperative analgesia using a bupivacaine-fentanyl mixture via PCEA. Analgesic efficacy was assessed using the visual analog scale (VAS), total drug consumption, number of PCEA demands and successful attempts, and time to first rescue analgesic request.

Results: Resting VAS pain scores decreased progressively over time, from 3.96 ± 0.49 at baseline (H0) to 2.1 ± 0.76 at 24 hours and 1.54 ± 0.78 at 72 hours postoperatively (p < 0.05). Mean bupivacaine and fentanyl doses were highest on the first postoperative day and declined on subsequent days. The mean number of PCEA demands peaked on postoperative day one (15.36 ± 2.31 attempts). The mean time to first rescue analgesic request was 10.25 ± 2.09 hours.

Conclusions: Patient-controlled epidural analgesia using a bupivacaine-fentanyl mixture provides effective postoperative pain control in patients following renal transplantation

Tài liệu tham khảo

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3. Hoang Anh Trung, Hoang Thi Mien, Mai Thi Hien et al., “Association between anemia and clinical characteristics in post-renal transplant patients at Military Hospital 103”, Journal of Military Medicine and Pharmacy, 49 (5), 172-181, 2024.

4. Nguyen Trung Kien, Efficacy of patient-controlled thoracic epidural analgesia using bupivacaine-fentanyl mixture following upper abdominal surgery in elderly patients. Doctoral dissertation, 108 Institute of Clinical Medical and Pharmaceutical Sciences, 2014.

5. Nguyen Hong Thuy, Postoperative analgesic efficacy of continuous ultrasound-guided thoracic paravertebral block using bupivacaine-sufentanil mixture in patients undergoing nephroureterectomy. Doctoral dissertation, Hanoi Medical University, 2018.

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8. Tran Hoai Nam, Hoang Van Chuong, “Evaluation of analgesic efficacy of thoracic epidural analgesia using ropivacaine combined with fentanyl via patient-controlled administration following abdominal surgery”, Vietnam Medical Journal, 502 (2), 17-30, 2021.

9. Misiran K.B., Yahaya L.S.B, “The effectiveness of patient- controlled epidural analgesia with ropivacaine 0.165% with fentanyl 2.0 micro g/ml or levobupivacain 0,125% with fentanyl 2.0 micro g/ml as a method of postoperative analgesia after major orthopedic surgery”, Middle East J Anaesthesiol, 22 (1), 59-64, 2013.

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Tải xuống

Đã Xuất bản

31.05.2026

Cách trích dẫn

Tran Dac Tiep, Trinh Van Duc, Nguyen Ngoc Thach, Nguyen Truong An, & Truong Xuan Bach. (2026). EVALUATION OF ANALGESIC EFFICACY FOLLOWING RENAL TRANSPLANTATION USING BUPIVACAINE-FENTANYL MIXTURE VIA PATIENT-CONTROLLED EPIDURAL ANALGESIA. Tạp Chí Y học Quân sự, (384), 9–14. https://doi.org/10.59459/1859-1655/JMM.835

Số

Chuyên mục

NGHIÊN CỨU - TRAO ĐỔI
 Ngày nhận bài      03-09-2025
 Ngày xuất bản      31-05-2026

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