INTRODUCTION OF A CLINICAL CASE OF COVID-19 SEVERE LUNG INJURY, TREATED BY CORTICOID
Từ khóa:
Corticoid treat COVID-19, lung injuriesTóm tắt
COVID-19 epidemic appeared at the end of 2019 and it became a global pandemic. That disease was caused by the SARS-CoV-2 virus. There are 20% COVID-19 patients that were hospitalized and 5% lung injury had respiratory failure. Lung injuries that appeared IIA stage were treated by corticoid to significantly improve clinical and subclinical criteria. A severe COVID-19 patient had severe pneumonia (respiratory rate 30 b/m, SpO2 82% with room air, PaO2 67 mmHg, P/F 319, X-ray bilateral diffused consolidated injuries), treated methylprednisolone 1.5 mg/kg/day combined with antibiotics, anticoagulant… The patient gradually recovered, improved clinical criteria, decreased lung injuries on X-ray, discharged after 14 days.
Tài liệu tham khảo
Lopez Zuniga M.A (2021), “High-dose corticosteroid pulse therapy increases the survival rate in COVID-19 patients at risk of hyper-inflammatory response”, PLoS One, 16 (1): p. e0243964.
Amy H Attaway, Adarsh Bhimraj (2021), “Severe covid-19 pneumonia: pathogenesis and clinical management”, The BMJ, 372: p. 19.
Ko J.J (2021), “A comparison of methyl-prednisolone and dexamethasone in intensive care patients with COVID-19”, MedRxiv, p. 1-22.
Janet V Diaz, Nedret Emiroglu (2020), “Corticosteroids for COVID-19”, WHO, 1: p. 25.
Ranjbar (2021), “Methylprednisolone or dexamethasone, which one is superior corticosteroid in the treatment of hospitalized COVID-19 patients: a triple-blinded randomized controlled trial”, BMC Infect Dis, 21 (1): p. 337.
Ministry of Health (2021), Guidelines for diagnosis and treatment of COVID-19 caused by a new strain of Corona virus, Hanoi, p. 24.
Edalatifard (2020), “Intravenous methyl-prednisolone pulse as a treatment for hospitalised severe COVID-19 patients: results from a randomised controlled clinical trial”, Eur Respir J, 56 (6).
Pinzon (2021), “Dexamethasone vs methyl-prednisolone high dose for COVID-19 pneumonia”, PLoS One, 16 (5): p. e0252057.
Monreal (2021), “High versus standard doses of corticosteroids in severe COVID-19: a retrospective cohort study”, Eur J Clin Microbiol Infect Dis, 40 (4): p. 761-769.
